Well, I have WfW 3.11 in a DosBox environment. The sound card support was tricky, but I did get it going. I also have DOS 6.22, and FreeDOS installed for DosBox. To be honest, fiddling with the autoexec.bat and config.sys files gives me a headache.
All of that, plus Windows ME and Windows 8.0 are the primary reasons that I love my Linux! I do, however, still enjoy tinkering with some older versions of Windows, and I also have some older software that won't run right in newer versions of Windows.