The unwound strings must be awkward as the gut seems to dry out, probably why they were twisted directly after the sheeps' slaugheter. Once twisted I think they should retain their flexibility better.
I forgot also that longcase (Grandfather) and Vienna clock lines were traditionally made from gut. I used it in my clock but often substituted a twisted nylon look-alike when repairing other people's clocks if I knew they were not going to look after the timepiece. I made my clock about 18 years ago and have only applied a little oil to the lines twice since. There's no sign of wear or fraying though mine runs with two 10lb weights whereas others can use up to 14lbs each side. It seems the longcase lines can last for 50 years or more.