
Originally Posted by
ab1ga
I too would like to find such a site, but the Holy Grail seems an easier project just now.
I can give some input to one of your questions, though. While breeding is used to generate strains with improved characteristics, it has three limitations. The first is time, since you have to go through a generation to figure out how a cross worked. The second is cost, which is related to the first because breeding generally involves whole plants, whereas genetic modification can be done on lots of different plant cells at once. Finally, conventional breeding does not easily allow for cross-species breeding.
The ability to transfer genes across species lines is where the greatest potential, but also the capability for harm comes in. Plants don't like to be eaten by bugs, so some species have developed the ability to synthesize natural insecticides to discourage pests. Through breeding one can increase the amount of pesticide produced, but at what point is it too much? There was an incident involving celery many moons ago. In most plants the pesticide is concentrated just below the skin, where it does the most good; in celery it is more uniformly dispersed throughout the entire plant. If you peel or thoroughly wash your food, you can reduce the toxin load, but not so with celery. It seems someone bred a super-resistant celery which had been amped up enough to actually make people sick, and the strain was pulled from the market.
I believe that celery was a product of natural breeding, but things can get trickier when you go cross-species, because you can't necessarily tell how active a specific gene will be in a totally different host. Even if things look good in lab testing, you can't reproduce all of the different growing conditions the plant will see (although companies do a hell of a job designing the experiments, with good results), and the activity of a gene may be dependent on soil or temperature conditions.
And remember, if the purpose of the modification is to increase resistance to disease or insects, that means the plant is producing poisons. If you wanted to try out a new drug on people, extensive EPA testing is long and arduous, but a chemical with toxic effects not generally administered to humans can be introduced into foods with much less safety testing. That is, I believe, the main source of rational objections to the blanket acceptance of GM foods. This doesn't even address the impact such organisms could have on other plants growing in the area.
73,