I took Pristiq for 2 months. I determined that it was simply worthless snake oil. It did absolutely nothing. When Prozac was all the rage, I was able to determine through raw testing that it was made up of analogous substances to cocaine and heroin. It was a speedball for the masses.
Had a friend who took Paxil for a few days. It made him dumber than a box of rocks, ornerier than a mule and as giggly as a school girl.
Your Mileage May Vary.